Neuroscience research reveals that natural psychedelic compounds, such as psilocybin, increase connectivity and neuroplasticity in key regions of the brain. From a subjective perspective, this can allow people to break out of negative “loops” or thought patterns and form new narratives about their lives. It can also create opportunities for introspective insights and shifts in perspectives.

Psychedelic medicines have been designated as a “breakthrough therapy” by the FDA because initial research demonstrates greater efficacy over existing treatment options. Researchers have discovered that these compounds work very differently than traditional psychiatric medications such as SSRIs.

“If you compare mental health care with any other branch of medicine—infectious disease, cardiology, oncology—there have been very few achievements. Mental health treatment has not lengthened the human life span. We need some new thinking, we need some new ideas, and psychedelics may well be that new idea.”

Michael Pollan, author of How to Change Your Mind

Learn more about how natural psychedelic medicine therapy works:

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Massachusetts has emerged as a national leader in psychedelic science and research with centers at Dana-Farber Cancer Institute, Mass General Hospital, and other leading medical institutions.

Safety and risk reduction: Natural psychedelic therapy is not for everyone

Natural psychedelic medicines are powerful, and like any treatment, there are risks. Question 4 will create a regulated program with mandatory safety screenings to determine if psychedelic therapy is a good fit for prospective participants. It’s important for anyone who is considering taking psychedelic medicines to be educated about risk factors and contraindications. Visit the University of California UC Berkeley Center for the Science of Psychedelics for more information.